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Get Your Free InertSustain C18 Column

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HPLC, LC/MS Column Catalog

Inertness and durability combined in a new HPLC column

GL Sciences newly developed technologies has enabled the modification of pore size, and its homogeneity, along with the amount of silanol groups of the base silica to be adequately controlled for each ligand in a variety of phases and applications.

This evolved surface silica (ES Silica) allows GL Sciences InertSustain™ Series to have a wide portfolio with extremely inert, chemical sustainability and batch to batch reproducibility for state-of-the-art analysis.


While other columns show poor peak shape, insufficient separation efficiency often with secondary interactions, and unsuitable physical properties of base silica that result in poor reproducibility. 

InertSustain™ Series delivers symmetric peaks with high efficiency.

Can be used for wide pH analysis with consistent performance

Superior inertness to typically any analytes

High efficiency

Extremely low operating back pressure

Compatibility with a wide range of solvents

Trusted By 

Leading Brands


“The columns are stable in a wide range of pH and perfectly suitable for separations followed by MS detection.  Compared with other columns such as Synergy Hydro-RP (from Phenomenex) or several columns from Waters dedicated for the separation of hydroxy acids, the separation and the peak shape obtained on the GL Sciences AQ-C18 column were better.”   

Dr. Serban Moldoveanu / Principal Scientist

R.J. Reynolds

InertSustain™ C18 Column

Tailing of peaks or adsorption of peaks can be experienced when a C18 column has residual adsorption sites. Such phenomenon would not be observed on InertSustain as the silanols are completely end-capped, having a neutral silica surface.

High Quality & Performance


pH Analysis

Low Back


Reliable Reproducibility